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Editorial MeSH terms Animals Clenbuterol / adverse effects* Clenbuterol / therapeutic use Horse Diseases / drug therapy Horses / physiology* Physical Conditioning, Animal / physiology* Sympathomimetics / adverse effects* Sympathomimetics / therapeutic use Time Factors Substances Sympathomimetics Clenbuterol. Clenbuterol is a sympathomimetic amine used by sufferers of breathing disorders as a decongestant and bronchodilator. People with chronic breathing disorders such as asthma use this as a bronchodilator to make breathing easier. It is most commonly available as the hydrochloride salt, clenbuterol hydrochloride. September 5, 2012 Clenbuterol, a beta-2-adrenoceptor agonist and the only FDA-approved medication for horses with reversible bronchospasm, is commonly used to treat horses with inflammatory. Clenbuterol, a beta-2-adrenoceptor agonist and the only FDA-approved medication for horses with reversible bronchospasm, is commonly used to treat horses with inflammatory airway disease (IAD). In response to the same parameters (i. , 5 mg of clenbuterol and sampled at 12 h), skeletal myocyte necrosis was 4. 8% in the soleus. These data show significant myocyte-specific necrosis in the heart and skeletal muscle of the rat. Such irreversible damage in the heart suggests that clenbuterol may be damaging to long-term health. Citations: 20 PDF Tools Share Abstract Long‐term administration of the β 2 ‐adrenergic agonist clenbuterol in mdx mice was used to test the hypothesis that increasing contractile protein content in skeletal muscle will decrease the progression of muscular dystrophy


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